Bonefix

Functional Nanostructured Implant for Bone Fixation-COFUND-ERANET MANUNET III PN3-P3-302 Contract 99-2019

Abstract of the project

The project objective is to obtain orthopaedic implants from a new biomaterial (Gum alloy) nanostructured by Severe Plastic Deformation having antibacterial nanocoatings. The project provides advanced solution with powerful societal impact by developing temporary implants, new compression staples with multidirectional gripping, able to ensure better fixation of bone fragments especially at the multiple fractures. For achieving project goals, scientific activities will be developed concerning the following: design of the alloy composition; alloy synthesis; study of the alloy deformability; thermomechanical alloy processing by High Speed High Pressure Torsion; complex characterization of the ascast/ processed alloy; antibacterial nanostructured coatings deposition; invitro advanced characterization by electrochemical studies to asses the corrosion behaviour of the alloy and of the coatings; invitro characterization by biological cellular response analysis; finally, implants design and execution. In addition, the project aims to demonstrate the applicability of the research results and validation both manufacturing and characterizing technologies on a number of test implants.