Project title:

Functional Nanostructured Implant for Bone Fixation

Project acronym:

BoneFix

Abstract of the project

The project objective is to obtain orthopaedic implants from a new biomaterial (Gum alloy) nanostructured by Severe Plastic Deformation having antibacterial nanocoatings. The project provides advanced solution with powerful societal impact by developing temporary implants, new compression staples with multidirectional gripping, able to ensure better fixation of bone fragments especially at the multiple fractures. For achieving project goals, scientific activities will be developed concerning the following: design of the alloy composition; alloy synthesis; study of the alloy deformability; thermomechanical alloy processing by High Speed High Pressure Torsion; complex characterization of the ascast/ processed alloy; antibacterial nanostructured coatings deposition; invitro advanced characterization by electrochemical studies to asses the corrosion behaviour of the alloy and of the coatings; invitro characterization by biological cellular response analysis; finally, implants design and execution. In addition, the project aims to demonstrate the applicability of the research results and validation both manufacturing and characterizing technologies on a number of test implants.

The project objective

This project aim to obtain compression staples from a new Gum type biomaterial, with advanced properties, able to ensure better fixation of bone fragments, especially at the multiple fractures. The main goal is the development at laboratory scale of an innovative reliable technology to obtain multidirectional gripping compression staples, from a superelastic high biocompatible Ti alloy, by the experimental development of HSHPT method. The new HSHPT technique allows to obtain in the same time the implant shape and ultrafinegrained to nanocrystalline bulk structure, directly from the cast Ti alloy. In this way, it reduces the production flow as compared to the classical route, because from as cast alloy is obtained the semiproduct with an ultrafine structure in a shape from which are cut directly the compression staples.

Expected results

BoneFix will have two category of results first one refers to a superelastic (Gum type) bioalloy with high biocompatibility, for temporary implant body and multidirectional compression staples with fine/ ultrafine structure and antibacterial nanocoatings. The second one refers to a new technology chains for temporary implants respectively synthesis of bulk Gum type alloy, thermomechanical processing (SPD) implant manufacturing and antibacterial surface coatings deposition.

Consortium

"DUNAREA DE JOS" UNIVERSITY OF GALATI - project coordinator

R&D Consulting and Services- partner 2

UNIVERSITY OF BUCHAREST- partner 3

INGENIERÍA NAVARRA MECÁNICA- partner 4

Project duration

May 2019- November 2020

Financial data

582.500 lei National Budget

60.580 Partner contribution

Funding agency

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii.